9th RSC / SCI symposium on kinase inhibitor design
Monday-Tuesday, 1st-2nd June 2020
The Francis Crick Institute, London, UK
Registration is open
Twitter hashtag - #Kinase20
|Downloads and Links|
Oral and poster abstract template - closing dates are 18th December (oral) and 17th April (poster)
Accommodation booking weblink - release date is 3rd April
With more than 49 FDA-approved small molecules, the field of kinase inhibition continues to attract significant investment from the drug discovery and development community. The 9th RSC/SCI symposium on kinases will encompass plenary lectures on emergent topics and case studies of ongoing programmes as well as successful past programmes. A range of topics including new screening approaches, brain penetrant kinase inhibitors, induced protein degradation, allosteric inhibitors and kinase inhibition for immuno-oncology will be covered, along with views and perspectives on the future of kinase inhibitor research.
Who should attend?
Call for Papers
Abstracts are invited for oral and poster presentation. Posters will be displayed throughout the meeting, and a dedicated poster session. There will also be an option for a flash oral presentation (two minutes, single slide).
Closing dates for submissions are 18th December (oral) and 17th April (poster).
Structure-based design of selective CaMK1 inhibitors
Sam Butterworth, The University of Manchester, UK
Exploiting the kinase conformational repertoire for allosteric regulation of IRE1α kinase-endoribonuclease
Ian Collins, The Institute of Cancer Research, UK
Protein degradation of kinases with PROTACs: a route to differentiated medicines?
John Harling, GlaxoSmithKline, UK
The shape-shifting protein kinases
Peter Parker, The Francis Crick Institute, UK
Discovery of AZD8154, a dual PI3Kγδ inhibitor, as an inhaled treatment for asthma
Matthew Perry, AstraZenca, SE
Structure-based drug design of selective WEE1 inhibitors
Fragment-based discovery of small molecule MRCK inhibitors
Mairi Sime, Beatson Drug Discovery Unit, UK
The design of CNS-penetrant molecules for therapeutic utility: design strategies and case studies
Sarah Skerratt, MSD, UK
Fragment-derived, selective and orally-active inhibitors of DYRK1A and DYRK1B
Application of FragLites to druggability and hit finding
Registration, Fees and Bursaries
Online registration - to pay by card - link to be created
Registration is open and fees include Monday evening's drinks reception.
Early rates for payments received by 26th February
* Member is paid-up member of the RSC or SCI.
Discounted rates are available for RSC and SCI student members, and some student bursaries will also be available. The closing date will be 15th April.
In the event of cancellation by 17th May 2020, 80% of the fee paid will be refunded. Cancellations must be received in writing. Refunds will not be possible after that date although substitutions are possible at any time. In the unlikely event of cancellation of the meeting, fees paid will be refunded in full.
There will be a relevant trade exhibition and the charge is £990. This rate includes:
- stand space measuring 3 m wide x 2 m deep
- trestle table measuring 1.8 m wide x .8 m deep
- access to electricity and wi-fi
- inclusion of a promotional slide to be played in rotation on the main screen during breaks
- one full delegate with all catering.
Delegate pack inserts may be booked at £250 - no more than two sheets of A4 fixed together.
We are grateful to our confirmed sponsors
We are grateful to our supporters below
Venue and Travel
Address: The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK
Centrally located adjacent to King’s Cross St Pancras railway station, the Institute is readily accessible by public transport.
A number of bedrooms have been held (via InCorporate Venues) at the Travelodge Kings Cross Royal Scot and the Travelodge Central Euston. Rooms are available to book online via this link. Details are below.
Kings Cross Royal Scot, WC1X 9DT
Release date: 3rd April 2020 at midday
Travelodge Central Euston, NW1 1DJ
£81.60 Sunday, 31st May per room + £6.30 per person for breakfast
Booking weblink here
Maggi Churchouse Events, 3 East Barn, Market Weston Road, Thelnetham, Diss IP22 1JJ, UK
Telephone: +44 (0)1359 221004