Kinase 2020:

9th RSC / SCI symposium on kinase inhibitor design


Monday-Tuesday, 1st-2nd June 2020

The Francis Crick Institute, London, UK



Registration is open


Twitter hashtag - #Kinase20


Downloads and Links

Online registration - to pay by card

Registration form - for payment by bank transfer or cheque


First announcement

Oral and poster abstract template - closing dates are 18th December (oral) and 17th April (poster)


Venue location weblink

Accommodation booking weblink - release date is 3rd April


RSC website

SCI website



With more than 49 FDA-approved small molecules, the field of kinase inhibition continues to attract significant investment from the drug discovery and development community. The 9th RSC/SCI symposium on kinases will encompass plenary lectures on emergent topics and case studies of ongoing programmes as well as successful past programmes. A range of topics including new screening approaches, brain penetrant kinase inhibitors, induced protein degradation, allosteric inhibitors and kinase inhibition for immuno-oncology will be covered, along with views and perspectives on the future of kinase inhibitor research.


Programme Themes
This event will bring together industrial and academic experts representing many of the leading institutions in kinase drug discovery, to discuss a selection of new and emerging topics within the fields of kinase therapeutics for oncology and non-oncology therapies, and foster discussions within the wider industry through networking events such as poster sessions and industrial exhibitions.


Who should attend?
This event is aimed at all scientists interested in furthering their knowledge of kinases. It will also have wider appeal to members of the drug discovery community eager to understand how enzyme inhibitor programmes are approached and executed across the pharmaceutical industry. 


Call for Papers

Abstracts are invited for oral and poster presentation. Posters will be displayed throughout the meeting, and a dedicated poster session. There will also be an option for a flash oral presentation (two minutes, single slide).


Please download an abstract template here.

Closing dates for submissions are 18th December (oral) and 17th April (poster).


Confirmed Speakers

Structure-based design of selective CaMK1 inhibitors

Sam Butterworth, The University of Manchester, UK


Exploiting the kinase conformational repertoire for allosteric regulation of IRE1α kinase-endoribonuclease

Ian Collins, The Institute of Cancer Research, UK


Protein degradation of kinases with PROTACs: a route to differentiated medicines?

John Harling, GlaxoSmithKline, UK

X-ray structures and feasibility assessment of CLK2 inhibitors for Phelan McDermid syndrome
Andreas Lerchner, Novartis, CH


The shape-shifting protein kinases

Peter Parker, The Francis Crick Institute, UK


Discovery of AZD8154, a dual PI3Kγδ inhibitor, as an inhaled treatment for asthma

Matthew Perry, AstraZenca, SE

Structure-based drug design of selective WEE1 inhibitors
Tom Pesnot, Concept Life Sciences, UK


Fragment-based discovery of small molecule MRCK inhibitors

Mairi Sime, Beatson Drug Discovery Unit, UK


The design of CNS-penetrant molecules for therapeutic utility: design strategies and case studies

Sarah Skerratt, MSD, UK

Fragment-derived, selective and orally-active inhibitors of DYRK1A and DYRK1B
Lee Walmsley, Vernalis Research, UK

Application of FragLites to druggability and hit finding
Mike Waring, Newcastle University, UK


Registration, Fees and Bursaries

Online registration - to pay by card - link to be created

Registration form - for payment by bank transfer or cheque


Registration is open and fees include Monday evening's drinks reception.


Early rates for payments received by 26th February
£270 RSC or SCI member*
£335 Non-member
£130 RSC or SCI student** member
£155 Student** non-member

Standard rates for payments received between 27th February and 29th April
£335 RSC or SCI member*
£400 Non-member
£165 RSC or SCI student** member
£190 Student** non-member

Late rates for payments received from 30th April onwards
£50 Late payment fee to be added to the above standard rates


*   Member is paid-up member of the RSC or SCI.
**  Student is undergraduate or post-graduate, not post-doc, and does not apply to students in paid employment.

Discounted rates are available for RSC and SCI student members, and some student bursaries will also be available.  The closing date will be 15th April. 


Cancellation Policy

In the event of cancellation by 17th May 2020, 80% of the fee paid will be refunded. Cancellations must be received in writing. Refunds will not be possible after that date although substitutions are possible at any time. In the unlikely event of cancellation of the meeting, fees paid will be refunded in full.


There will be a relevant trade exhibition and the charge is £990. This rate includes:

- stand space measuring 3 m wide x 2 m deep

- trestle table measuring 1.8 m wide x .8 m deep

- access to electricity and wi-fi

- inclusion of a promotional slide to be played in rotation on the main screen during breaks
- logo acknowledgement in the delegate handbook

- one full delegate with all catering.


Delegate pack inserts may be booked at £250 - no more than two sheets of A4 fixed together.



We are grateful to our confirmed sponsors






We are grateful to our supporters below



Venue and Travel

Address:  The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK


Centrally located adjacent to King’s Cross St Pancras railway station, the Institute is readily accessible by public transport.


Venue location weblink



A number of bedrooms have been held (via InCorporate Venues) at the Travelodge Kings Cross Royal Scot and the Travelodge Central Euston.  Rooms are available to book online via this link.  Details are below.


Kings Cross Royal Scot, WC1X 9DT
£50.70    Sunday, 31st May per room + £6.30 per person for breakfast
£86.75    Monday, 1st June per room + £6.30 per person for breakfast

Release date: 3rd April 2020 at midday

Travelodge Central Euston, NW1 1DJ

£81.60     Sunday, 31st May per room + £6.30 per person for breakfast
£153.70    Monday, 1st June per room + £6.30 per person for breakfast
Release date: 3rd April 2020 at midday

Booking weblink here
Any unbooked bedrooms will be released at midday on 30th April , and cancellation will not be possible thereafter.


Organising Committee

John CummingF Hoffmann-La Roche
John HarrisCJH Consultants
Pascal Savy (chair)Charles River
Mihiro SunoseSygnature Discovery
Richard WardAstraZeneca
Douglas WilliamsonVernalis Research


Secretariat Contact

Maggi Churchouse Events, 3 East Barn, Market Weston Road, Thelnetham, Diss IP22 1JJ, UK

E-mail Maggi Churchouse

Telephone: +44 (0)1359 221004


Registration is open