31st symposium on

Medicinal Chemistry in Eastern England


Thursday 26th November 2020



A virtual event

Registration closed at midday on Thursday, 19th November


Twitter hashtag #HatfieldMedChem20 


Downloads and Links


RSC website

RSC special offer on membership - follow this link to see below

Registration closed at midday (UK time) on Thursday, 19th November

Delegate handbook - for registered delegates only, password-protected


Medium - this virtual event will be hosted on the GoToWebinar platform


The Symposium on Medicinal Chemistry in Eastern England, known colloquially as the "Hatfield MedChem" meeting, is a highly successful, long-standing, one-day meeting which runs annually. The scientific programme will comprise presentations showcasing medicinal chemistry case studies from tools to candidates, across a range of modalities, therapeutic areas and target classes, as well as covering more general topics from the forefront of drug discovery of relevance to medicinal chemists. The meeting aims to be informal and interactive and the event will offer excellent scientific and networking opportunities for all those working in medicinal chemistry and drug discovery.


There is no poster abstract opportunity for this virtual event.  Instead any abstracts will be considered for the virtual 32nd symposium, to be held at the Fielder Centre, Hatfield on Thursday, 29th April 2021.


Registration closed at midday (UK time) on Thursday, 19th November


Registration fees were:

£50  RSC member

£75  Non-member

£27  RSC student* member

FOC Retired RSC member

*  Student is an undergraduate or post-graduate, but not a post-doc.


Cancellation Policy
In the event of cancellation by 5th November 2020, 80% of the fee paid will be refunded. Cancellations must be received in writing. Refunds will not be possible from 6th November although substitutions are possible at any time.

In the unlikely event of cancellation of the meeting, fees paid will be refunded in full.  Registration acknowledgements will be sent within two weeks.


RSC Special Offer on Membership


We know that not everyone in the audience is a member of the Royal Society of Chemistry and there may be several reasons for this, but right now the RSC are offering free Affiliate membership to anyone who attends one of our online events. If you’ve ever considered joining but haven’t got around to it, or are not sure what you could get out of being a member, then maybe now is the time to sign up as an Affiliate for free and try it out.

Affiliate membership doesn’t need a degree transcript or CV, simply go to rsc.li/affiliate and use the discount code IG100 to join, and then you can become a member of our Interest Group, the BMCS, and keep up to date with all of our events and activities.

Affiliate membership offers:
- Free membership of one Interest Group*
- 10 free RSC journal article downloads a year and 35% off RSC books
- Online access to Chemistry World
- Access to careers resources and webinars and discounts for accredited training courses
- Support from the Chemists’ Community Fund
- Discounts on travel, insurance, lifestyle and publications.
* You may wish to choose the BMCS (Biological and Medicinal Chemistry Sector)!



Welcome and introduction


Session Chair - Diane Coe, GlaxoSmithKline


PROTACs as biological tools and achieving bioavailability beyond the Rule of Five

Daniel O'Donovan, AstraZeneca


Safe, effective and versatile devices for photoredox chemistry: light at the end of the tunnel
Arran Solomonsz, Asynt


Discovery of a novel series of small molecule modulators of TNFα binding and signalling

Dan Brookings, UCB


Refreshment break

10.50Structure-based drug design of Calcitonin Gene-Related Peptide (CGRP) receptor antagonists
Andrew Cansfield, Sosei Heptares

Prep HPLC from Teledyne ISCO: Taking the hard work out of method development with our new focused gradient generator
Lisa Sargeant, Teledyne ISCO


The Power of One … discovery of the first selective and non-covalent small molecule inhibitors of DNMT1
Ali Raoof, Drug Discovery Unit, Cancer Research UK Manchester Institute



Lunch break

12.30Networking session - meet the speakers

Session Chair - Simon Ward, Cardiff University


Capps Green Zomaya Award presentation lecture

Molecular simulation strategies for ensemble-based drug design

Julien Michel, University of Edinburgh


The challenges of targeting RNA modifying enzymes as drug targets
Wesley Blackaby, Storm Therapeutics


Building a PROTACs toolbox for contract research
Tom Coulter, Selvita


Expanding the medicinal chemist’s tool box: recent highlights in synthetic chemistry

Robert Griffiths, Charles River


Refreshment break


Design and synthesis of Janus kinase inhibitors for inhaled delivery and the importance of aldehyde oxidase metabolism in the lung

Christopher Wellaway, GlaxoSmithKline


Cartridge-based automated synthesis – a new tool for the medicinal chemist
Paula Nichols, Synple Chem


Key aspects of fragment-based drug discovery and structure-based drug design strategies from the development of PPI clinical compounds

Louise Walsh, Astex Pharmaceuticals

16.25Concluding remarks


Networking session - meet the speakers



The Exhibition Opportunity Package comprises promotional page and logo linked to your chosen webpage in the electronic delegate handbook, and logo in rolling slides shown during the breaks.  The charge is £60 and no registration is included.


Confirmed Exhibition Opportunity organisations are listed below.  Each company name is weblinked to their preferred webpage:

- Activate Scientific

- Activotec

- ApconiX

- Apollo Scientific
- Asynt

- BioAscent Discovery
- Biopharma Group
- Biotage AB, from Sweden

- BLD Pharmatech

- Buchi UK
- CEM (Microwave Technology)
- ChemBridge Corporation

- Concept Life Sciences
- Cyprotex Discovery

- Domainex

- High Force Research
- Hypha Discovery

- IKA England
- Key Organics
- Liverpool ChiroChem

- MedChemica

- Raybow

- Reach Separations

- Schrödinger

- Science Solutions Recruitment
- Selvita
- Strem
- Synple Chem
- Teledyne ISCO

- Thermo Fisher Scientific

Invited Exhibitor Speaker comprises a registration fee with five-minute speaking slot, plus the above Exhibition Opportunity Package - fully booked.


Sponsors are encouraged to support this popular event, and we are grateful to our confirmed sponsors for their kind support.











Organising Committee
Adrian Hall, UCB (treasurer)
Nicole Hamblin, Charles River (chair)
David Hirst, GlaxoSmithKline


Secretariat Contact
Maggi Churchouse, 3 East Barn, Market Weston Road, Thelnetham, Diss IP22 1JJ, UK
Telephone: +44 (0)1359 221004
E-mail:  maggi@maggichurchouseevents.co.uk


Registration is closed


Link to return to the RSC BMCS index page