31st symposium on

Medicinal Chemistry in Eastern England


Thursday 30th April 2020

The Fielder Centre, Hatfield, Hertfordshire, UK



Registration is open


Twitter hashtag #HatfieldMedChem20 


Downloads and Links

Online registration - for payment by card
Registration form - for payment by bank transfer or cheque



Poster abstract template - closing date is 30th March

Bursary application form - closing date is 26th March


Directions to the Fielder Centre
Accommodation suggestions
RSC website


The Symposium on Medicinal Chemistry in Eastern England, known colloquially as the "Hatfield MedChem" meeting, is a highly successful, long-standing, one-day meeting which runs annually. The scientific program will comprise presentations showcasing medicinal chemistry case studies from tools to candidates, across a range of modalities, therapeutic areas and target classes, as well as covering more general topics from the forefront of drug discovery of relevance to medicinal chemists. The meeting aims to be informal and interactive and the event will offer excellent scientific and networking opportunities for all those working in medicinal chemistry and drug discovery.


Call for Posters
Abstracts are invited for poster presentation and the closing date for submissions is 30th March.  Please download an abstract template here.


Registration and Bursaries
Online registration - for payment by card
Registration form - for payment by bank transfer or cheque


Registration is open and fees are:

£100   RSC member

£150   Non-member

  £55   RSC student* member

    £0   Retired RSC member


* Student is undergraduate or postgraduate, not post-doc.

Some bursaries are available to help cover costs including registration fee and travel.


Please download a bursary application form here and note that the closing for submissions is 26th March.


Cancellation Policy
For cancellations received in writing by the Secretariat, 80% of the fee paid will be refunded for notifications received before 16th April. No refunds will be made for cancellations received from 17th April onwards, although substitutions are possible at any time. In the unlikely event of our cancelling the event, we will refund the registration fees paid in full.




Registration, refreshments, exhibition and posters


Welcome and introduction


Session Chair - Sharan Bagal, AstraZeneca


Discovery of development candidate DMXD-011 for the treatment of interferonopathies

Mark Stewart, Domainex


PROTACs as biological tools and achieving bioavailability beyond the Rule of Five

Daniel O'Donovan, AstraZeneca


Refreshments, exhibition, and posters


Discovery of a novel series of small molecule modulators of TNFa binding and signalling

Dan Brookings, UCB


Structure-based drug design of Calcitonin Gene-Related Peptide (CGRP) receptor antagonists
Andrew Cansfield, Sosei Heptares


The Power of One Ö discovery of the first selective and non-covalent small molecule inhibitors of DNMT1
Ali Raoof, Drug Discovery Unit, Cancer Research UK Manchester Institute


Lunch, exhibition and posters


Session Chair - Simon Ward, Cardiff University


Capps Green Zomaya Award presentation lecture

Presentation title to be confirmed

Sharan Bagal, AstraZeneca


The challenges of targeting RNA modifying enzymes as drug targets
Wesley Blackaby, Storm Therapeutics


Expanding the medicinal chemistís tool box: recent highlights in synthetic chemistry

Robert Griffiths, Charles River


Refreshments, exhibition and posters


Design and synthesis of Janus kinase inhibitors for inhaled delivery and the importance of aldehyde oxidase metabolism in the lung

Christopher Wellaway, GlaxoSmithKline


Key aspects of fragment-based drug discovery and structure-based drug design strategies from the development of PPI clinical compounds

Louise Walsh, Astex Pharmaceuticals


Concluding remarks




A relevant trade exhibition will add value to the symposium.  

Sorry, fully booked.


The exhibition will be held in the same room as the catering (refreshments and lunch) and posters.   An exhibition stand space only is charged at £250, and the package includes:
- chair and table, measuring 120 cm wide x 70 cm deep
- electrical access and wi-fi access

- your logo included in the printed delegate handbook, and in the rolling slides shown between sessions
- the option to include a promotional page for your organisation in the delegate handbook

£75   charge for exhibition stand staff, with no access to technical sessions.


The exhibition consistently sells out, so early booking is recommended.


Delegate pack inserts may be booked at £120, and the sponsor should provide the inserts comprising no more than two pages of A4 fixed together.


Venue and Travel
The symposium will be held in the Lecture Theatre at the Fielder Centre, Hatfield Business Park, Hatfield Avenue, Hatfield AL10 9TP.  Directional information may be found here, and this is a link to the venue's website.

The Fielder Centre can be reached easily by road, rail or air:
- Just off junction 4 of the A1(M)
- 5 minutes from the M25 motorway
- 10 minutes from the M1 motorway
- 30 minutes from London Luton and Stansted Airports
- 25 minute rail journey from London Kings Cross


Sponsors are encouraged to support this popular event, and we are grateful to Charles River for their kind support.










We are grateful to EFMC for supporting this event




Organising Committee
Adrian Hall, UCB (treasurer)
Nicole Hamblin, Charles River (chair)
David Hirst, GlaxoSmithKline


Secretariat Contact
Maggi Churchouse, 3 East Barn, Market Weston Road, Thelnetham, Diss IP22 1JJ, UK
Telephone: +44 (0)1359 221004
E-mail:  maggi@maggichurchouseevents.co.uk


Registration is open

Link to return to the RSC BMCS index page