30th symposium on

Medicinal Chemistry in Eastern England


Thursday 2nd May 2019

The Fielder Centre, Hatfield, Hertfordshire, UK



Registration is closed


Downloads and Links

Registration is closed, fully booked - sorry

Online registration - to pay by card

Registration form - to pay by bank transfer

To add your name to the waiting list and to be considered for any cancellations, please send a message to Maggi here.


Announcement and call for posters

Directions to the Fielder Centre
Accommodation suggestions
RSC website


2019 represents the 30th anniversary of the Symposium on Medicinal Chemistry in Eastern England, known colloquially as the "Hatfield MedChem" meeting. This is a highly successful, long-standing, one-day annual meeting. To commemorate 30 years, the programme will focus on ‘Celebrating UK Drug Discovery’, highlighting success stories from large pharma, biotech and academia; and exciting scientific prospects for the future. Presentations will showcase medicinal chemistry from tools to candidates, across a range of modalities, therapeutic areas and target classes with an emphasis on key learnings and knowledge developed during the course of effective discovery efforts. The meeting aims to be informal and interactive and will offer excellent scientific development and networking opportunities for all those working in medicinal chemistry and drug discovery.


Call for Posters
Abstracts were invited for poster presentation. The closing date for submission was 2nd March 2019. 


Registration and Bursaries
Registration is closed now - sorry.  The event is fully booked

Online registration - to pay by card

Registration form - to pay by bank transfer

To add your name to the waiting list and to be considered for any cancellations, please send a message to Maggi here.


Registration fees are:

£100  RSC member

£150   Non-member

  £55   RSC student* member
Free   Retired RSC member (limited places)
£250   Exhibition stand space only
  £75   Trade stand staff (no access to technical sessions) 
* Student is undergraduate or post-graduate, not post-doc

Some student bursaries were available, and the closing date for applications was 28th March. 





Registration, refreshments, exhibition and posters


Welcome and introduction

Nicole Hamblin, Charles River


Session Chair:  Jackie Macritchie, Charles River


Keynote Presentation: Drug discovery past, present and future: a personal perspective
Julian Blagg, Neophore and Azeria Therapeutics


A journey into CNS drug discovery

Tim Harrison, Almac Discovery


Refreshments, exhibition, and posters


Drugs from host-guest chemistry in Scotland and fragments in England

David Rees, Astex Pharmaceuticals


Multifunctional PROTACs: protein degradation with a twist

Ed Tate, Imperial College London and Crick Institute


Bicycles® - an entirely new class of therapies
Paul Beswick, Bicycle Therapeutics


Lunch, exhibition and posters


Session ChairSimon Ward, Medicines Discovery Institute, Cardiff University


Capps Green Zomaya Award presentation lecture

The covalent targeting of cysteine residues in drug discovery and its application to the discovery of Osimertinib

Richard A Ward, AstraZeneca


Discovery of three generations of selective beta-2 agonists, from salbutamol to vilanterol

Diane Coe, GlaxoSmithKline


Phenotypic activity driven target identification and discovery of drug candidates
Paul Wyatt, Drug Discovery Unit, University of Dundee


Refreshments, exhibition and posters


Collaborating through chemistry to find the right targets

Dafydd Owen, Pfizer Worldwide R&D


Application of structure-based drug discovery to G protein-coupled receptors
Miles Congreve, Sosei Heptares


When the rubber hits the road: a case study of AI applied to ALS Drug Discovery

Mark Rackham, BenevolentAI


Concluding remarks




A relevant trade exhibition will add value to the symposium.  


Sorry, fully booked.


Delegate pack inserts may be booked at £120.  These should comprise no more than two sheets of A4 fixed together (sponsor to supply).


Exhibition stand space only is priced at £250 excluding any attendees. The exhibition will be held in the same room as the catering (refreshments and lunch) and posters, and the exhibition package includes:
- chair and table, measuring 120 cm wide x 70 cm deep
- electrical access and wi-fi access

- your logo included in the printed delegate handbook, and in the rolling slides shown between sessions
- the option to include a promotional page for your organisation in the delegate handbook

The exhibition consistently sells out, so early booking was recommended.


Venue and Travel
The symposium will be held in the Lecture Theatre at the Fielder Centre, Hatfield Business Park, Hatfield Avenue, Hatfield AL10 9TP.  Directional information may be found here, and this is a link to the venue's website.

The Fielder Centre can be reached easily by road, rail or air:
- Just off junction 4 of the A1(M)
- 5 minutes from the M25 motorway
- 10 minutes from the M1 motorway
- 30 minutes from London Luton and Stansted Airports
- 25 minute rail journey from London Kings Cross


Cancellation Policy
For cancellations received in writing by the Secretariat, 80% of the fee paid will be refunded for notifications received before 18th April. No refunds will be made for cancellations received from 19th April onwards, although substitutions are possible at any time. In the unlikely event of our cancelling the event, we will refund the registration fees paid in full.


Sponsors were encouraged to support this popular event, and we are grateful to AstraZeneca and Evotec for their kind support.





We are grateful to EFMC for supporting this event




Organising Committee
Adrian Hall, UCB (treasurer)
Nicole Hamblin, Charles River (chair)
David Hirst, GlaxoSmithKline


Secretariat Contact
Maggi Churchouse, 3 East Barn, Market Weston Road, Thelnetham, Diss IP22 1JJ, UK
Telephone: +44 (0)1359 221004
E-mail:  maggi@maggichurchouseevents.co.uk


Registration is closed - fully booked